NCT00932347

Effect of Mouthwash Containing Camellia Sinensis Extracts on Oral Malodor

Effect of Mouthwash Containing Camellia Sinensis Extracts on Oral Malodor, Plaque and Papillary Bleeding Indices in Gingivitis Patients.

• Status: Completed
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 60 (estimated)
• Sponsor: Mahidol University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

The purpose of this study is to determine effect of Mouthwash containing Camellia sinensis extracts on oral malodor and gingival inflammation in gingivitis subjects.

Detailed description

At baseline, level of volatile sulfur compounds (VSC) in mouth air, Plaque Index and Papillary Bleeding Index will be recorded. Gingivitis subjects will be asked to rinse with Camellia sinensis mouthwash or placebo mouthwash. VSC level will be measured at 30 minutes and 3 hours post-rinsing. For the following 4 weeks, subjects will be rinsed with the assigned mouthwash twice daily after toothbrushing. All parameter will be recorded again at Day 28.

Conditions

• Gingivitis
• Halitosis

Interventions

Type	Name	Description
DRUG	Camellia sinensis mouthwash	mouthrinsing, 2 times/day, for 28 days
DRUG	Placebo mouthwash	mouthrinsing, 2 times/day, for 28 days

Timeline

• Start date: 2008-01-01
• Primary completion: 2009-09-01
• Completion: 2009-12-01
• First posted: 2009-07-03
• Last updated: 2011-07-22

Locations

2 sites across 1 country: Thailand