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CompletedNCT00913250

A Bioequivalence Study of Serum Free Avonex and Serum Containing Avonex in Healthy Volunteers

A Randomized, Single-Blind, Crossover Study in Healthy Volunteers to Demonstrate the Bioequivalence of AVONEX® (Interferon Beta-1a) Solutions for Injection Produced by a Serum-Containing Manufacturing Process and by a Serum-Free Manufacturing Process

Status
Completed
Phase
Phase 1
Study type
Interventional
Enrollment
96 (actual)
Sponsor
Biogen · Industry
Sex
All
Age
18 Years – 45 Years
Healthy volunteers
Accepted

Summary

Demonstrate the bioequivalence of a serum-free solution to a serum containing solution of Avonex.

Conditions

Interventions

TypeNameDescription
DRUGSerum containing Avonex60mcg IM dose of serum containing Avonex on Day 1, followed by 60mcg IM dose of serum free Avonex on Day 15
DRUGSerum Free Avonex60mcg IM dose of serum free Avonex on Day 1, followed by 60mcg IM dose of serum containing Avonex on Day 15.

Timeline

Start date
2003-08-01
Completion
2003-10-01
First posted
2009-06-04
Last updated
2009-06-04

Source: ClinicalTrials.gov record NCT00913250. Inclusion in this directory is not an endorsement.

A Bioequivalence Study of Serum Free Avonex and Serum Containing Avonex in Healthy Volunteers (NCT00913250) · Clinical Trials Directory