NCT00884338

Cognitive Function After Stem Cell Transplantation

Evaluation of the Cognitive Function of Patients After Stem Cell Transplantation

• Status: Unknown
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 60 (estimated)
• Sponsor: Charite University, Berlin, Germany · Academic / Other
• Sex: All
• Age: 18 Years – 70 Years
• Healthy volunteers: Not accepted

Summary

The trial will evaluate the effects of an exercise program on the physical and cognitive performance of patients with hematological neoplastic diseases after high dose chemotherapy with stem cell support.

Detailed description

Patients (n = 60) will be randomized to an exercise or a control group. The randomization will be stratified for allogeneic or autologous blood stem cell transplantation. Patients in the exercise group will carry out an endurance training consisting of walking on a treadmill at a speed corresponding to 80% of the maximum heart rate. The exercise program will be carried out 3 times weekly for 8 weeks. Patients in the control group will receive counseling about exercise and behavioural techniques to reduce fatigue, but they will not participate at a structured exercise program. Physical performance (VO2max), cognitive function, mood and quality of life will be evaluated at recruitment and after 8 weeks.

Conditions

• Fatigue
• Cognitive Impairment
• Stem Cell Transplantation

Interventions

Type	Name	Description
OTHER	Endurance exercise	The patients will carry out an endurance exercise program consisting of walking on a treadmill for 30 to 40 minutes at a speed corresponding to 80% of the maximum heart rate
OTHER	Counseling	Counseling about exercise and behavioural techniques to reduce fatigue

Timeline

• Start date: 2009-05-01
• Primary completion: 2011-08-01
• Completion: 2011-09-01
• First posted: 2009-04-20
• Last updated: 2009-12-21

Locations

1 site across 1 country: Germany