NCT00882492

GLP 1 for Intraoperative Glycemic Control

Identifying a Novel Mechanism for Perioperative Hyperglycemia Identifying a Novel Mechanism for Perioperative Hyperglycemia in Cardiac Surgery: A Role for Incretins

• Status: Completed
• Phase: Phase 1
• Study type: Interventional
• Enrollment: 80 (actual)
• Sponsor: University of Pennsylvania · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This is a medical research study designed to see if an infusion of a naturally occurring hormone, GLP-1, works when used to decrease blood sugar during cardiac surgery.

Conditions

• Hyperglycemia
• Hypoglycemia

Interventions

Type	Name	Description
BIOLOGICAL	GLP 1	This a continuous intravenous infusion of GLP-1 (7-36) amide infusion (1.5 pmol/kg/min)
BIOLOGICAL	normal saline solution placebo	This is a continuous intravenous infusion of normal saline solution as placebo (1.5 pmol/kg/min) during cardiac surgery

Timeline

• Start date: 2008-12-01
• Primary completion: 2011-05-01
• Completion: 2011-05-01
• First posted: 2009-04-16
• Last updated: 2012-02-16

Locations

1 site across 1 country: United States