Clinical Trials Directory

Trials / Completed

CompletedNCT00880308

Dose Finding and Safety of Oral LDE225 in Patients With Advanced Solid Tumors

A Phase I, Multicenter, Open-label, Dose-escalation Study of Oral LDE225 in Patients With Advanced Solid Tumors

Status
Completed
Phase
Phase 1
Study type
Interventional
Enrollment
103 (actual)
Sponsor
Novartis Pharmaceuticals · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

This first-in-human dose-escalation study is to characterize the safety, tolerability, pharmacokinetics and pharmacodynamics of LDE225 given orally on a daily dosing schedule in patients with advanced solid tumors.

Conditions

Interventions

TypeNameDescription
DRUGLDE225

Timeline

Start date
2009-03-01
Primary completion
2013-07-01
Completion
2013-07-01
First posted
2009-04-13
Last updated
2020-12-19

Locations

5 sites across 4 countries: United States, Spain, Switzerland, United Kingdom

Source: ClinicalTrials.gov record NCT00880308. Inclusion in this directory is not an endorsement.