Clinical Trials Directory

Trials / Completed

CompletedNCT00875992

Trial to Evaluate the Effectiveness of Angular Stable Locking System (ASLS) in Patients With Distal Tibial Fractures

A Randomized Controlled Trial to Evaluate the Effectiveness of Angular Stable Locking System (ASLS) in Patients With Distal Tibial Fractures Treated With Expert Tibial Nails (ETN)

Status
Completed
Phase
N/A
Study type
Interventional
Enrollment
141 (actual)
Sponsor
AO Clinical Investigation and Publishing Documentation · Academic / Other
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

In many cases, the existing locking bolts and screws in intramedullary nails do not provide sufficient stability. The play between screw and nail can result in loss of reduction and the instability due to the interfragmentary movement can result in malunions or nonunions. Therefore, an Angular Stable Locking System for Intramedullary Nails (ASLS) was developed to enhance axial and angular fracture stability. ASLS provides angular-stable fixation between nails and screws with resorbable sleeves used as dowels in the nail locking holes. Preliminary results of a pre-study show a trend towards reduced time to pain-free full weight bearing in patients being treated with ASLS. This hypothesis will be tested in the present randomized controlled study.

Detailed description

The primary aim of the present study is to evaluate the effectiveness of the Angular Stable Locking System (ASLS) in patients with distal tibial fractures treated with Expert Tibial Nails (ETN). In many cases, the existing locking bolts and screws in intramedullary nails do not provide sufficient stability. The play between screw and nail can result in loss of reduction and the instability due to the interfragmentary movement can result in malunions or nonunions. Therefore, an Angular Stable Locking System for Intramedullary Nails (ASLS) was developed to enhance axial and angular fracture stability. ASLS provides angular-stable fixation between nails and screws with resorbable sleeves used as dowels in the nail locking holes. Preliminary results of a pre-study show a trend towards reduced time to pain-free full weight bearing in patients being treated with ASLS. This hypothesis will be tested in the present randomized controlled study.

Conditions

Interventions

TypeNameDescription
DEVICEETN with ASLSAngle stable locking of ETN using ASLS
DEVICEETN locked with conventional locking boltsConventional surgical procedure

Timeline

Start date
2009-06-01
Primary completion
2012-08-01
Completion
2012-12-01
First posted
2009-04-06
Last updated
2013-01-23

Locations

8 sites across 3 countries: Austria, Germany, Norway

Source: ClinicalTrials.gov record NCT00875992. Inclusion in this directory is not an endorsement.