NCT00864487

Study Evaluating The Potential Effect Of Rifampin On The Pharmacokinetics Of Neratinib

A Study to Examine the Potential Effect of Rifampin on the Pharmacokinetics of Neratinib When Administered Concomitantly to Healthy Subjects

• Status: Completed
• Phase: Phase 1
• Study type: Interventional
• Enrollment: 24 (actual)
• Sponsor: Puma Biotechnology, Inc. · Industry
• Sex: All
• Age: 18 Years – 50 Years
• Healthy volunteers: Accepted

Summary

The purpose of this study is to examine whether co-administration of rifampin with neratinib has an effect on the pharmacokinetics (how the body absorbs, distributes, metabolizes and/or excretes) of neratinib.

Conditions

• Healthy Subjects

Interventions

Type	Name	Description
DRUG	Neratinib	HKI-272

Timeline

• Start date: 2009-04-01
• Primary completion: 2009-05-01
• Completion: 2009-05-01
• First posted: 2009-03-18
• Last updated: 2012-05-14

Locations

1 site across 1 country: United States