NCT00860236

Giardia Induced Fatigue and Functional Gastrointestinal Diseases

Chronic Fatigue Syndrome and Abdominal Symptoms After Giardia Infection: Clinical Evaluation, Biomarkers, Risk Factors and the Effect of Intervention

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 40 (estimated)
• Sponsor: University of Bergen · Academic / Other
• Sex: All
• Age: 18 Years – 70 Years
• Healthy volunteers: Not accepted

Summary

A giardiasis outbreak in Bergen has given us the opportunity to approach two basic research questions of national and global importance: * Studying the pathoimmunology of giardiasis in a natural setting, and following the genetic and immunological responses leading to recovery or persistent disease and sequelae. * Studying the two disease entities FGID and CFS when induced by acute giardiasi and their risk factors. * Interventional cognitive behavioural therapy is the only intervention documented to have significant effect on CFS outcome, and conventional cognitive behavioural therapy will be compared to a psycho-educational programme in the format of a randomised controlled trial.

Conditions

• Chronic Fatigue Syndrome

Interventions

Type	Name	Description
OTHER	Psycoeducation/counseling	2 days of education on mechanisms of illness and coping strategies
BEHAVIORAL	Cognitive behavioural therapy	4 days intensive training in understanding and behavioural changes

Timeline

• Start date: 2009-03-01
• Primary completion: 2010-06-01
• Completion: 2010-06-01
• First posted: 2009-03-12
• Last updated: 2017-03-03

Locations

1 site across 1 country: Norway