NCT00854256

Trabeculectomy Versus Canaloplasty to Treat Glaucoma

Comparison of Canaloplasty and Trabeculectomy in Patients With Open Angle Glaucoma and Inadequate Local Eye Pressure Lowering Therapy - a Prospective, Randomized Study

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 60 (estimated)
• Sponsor: University of Cologne · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The aim of the study is to investigate pressure lowering effect of two surgical methods canaloplasty and trabeculectomy in patients with open angle glaucoma, in which under local pressure lowering therapy the progression of the disease could not be stopped, and thus a pressure lowering surgical intervention is necessary. The risks in the postoperative course in Canaloplasty in the literature as lower than for the trabeculectomy with mitomycin-C. Conversely, large glaucoma centers questioning the effectiveness of permanent pressure lowering of canaloplasty. Precisely this question is investigated in the study.

Conditions

• Glaucoma

Interventions

Type	Name	Description
PROCEDURE	Canaloplasty	Canaloplasty surgery
PROCEDURE	Trabeculectomy with mitomycin C	Trabeculectomy with mitomycin C surgery

Timeline

• Start date: 2009-04-01
• Primary completion: 2013-12-01
• Completion: 2014-05-01
• First posted: 2009-03-03
• Last updated: 2013-04-15

Locations

1 site across 1 country: Germany