NCT00853073

Does Adding Bevacizumab Therapy in Glaucoma Surgery Improve the Success of Needle Bleb Revisions?

Does a New Add on (or Adjunctive) Therapy Used in Glaucoma Surgery Improve the Success of Needle Bleb Revisions?

• Status: Completed
• Phase: Phase 2 / Phase 3
• Study type: Interventional
• Enrollment: 63 (actual)
• Sponsor: Wills Eye · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to see if a new add on (or adjunctive) therapy used in glaucoma surgery improves the success of needle bleb revisions.

Detailed description

To investigate the efficacy of needle bleb revisions with mitomycin C with subconjunctival bevacizumab in promoting both filtering success and favorable bleb morphologic features.

Conditions

• Glaucoma

Interventions

Type	Name	Description
DRUG	bevacizumab	1.0mg (0.04 cc of 25 mg/ml subconjunctival bevacizumab following bleb needling procedure
OTHER	balanced salt solution	0.04 cc of balanced salt solution injected to the bleb following bleb needling procedure

Timeline

• Start date: 2009-02-01
• Primary completion: 2012-01-01
• Completion: 2012-01-01
• First posted: 2009-02-27
• Last updated: 2018-07-09
• Results posted: 2015-03-12

Locations

1 site across 1 country: United States