Trials / Completed
CompletedNCT00842023
Assessment of Biomarkers and Cardiorenal Syndrome in Acute Decompensated Heart Failure With Vasodilator Therapy
A Randomized Controlled Trial to Evaluate Renal Function, Inflammatory Mediators, and Neurohormonal Markers in Acutely Decompensated Heart Failure Patients Receiving Nesiritide Compared to Nitroglycerin.
- Status
- Completed
- Phase
- Phase 4
- Study type
- Interventional
- Enrollment
- 89 (actual)
- Sponsor
- Western University of Health Sciences · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
The purpose of this study is to determine whether Nesiritide is more effective than nitroglycerin in modifying inflammatory and neurohormonal biomarkers without renal toxicity when proper infusion duration is administered.
Detailed description
No additional details provided
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Nesiritide | Bolus 2 mcg/kg followed by 0.01 mcg/kg/min |
| DRUG | Nitroglycerin | 5-10 mcg/min titrating per protocol based on blood pressure |
Timeline
- Start date
- 2006-07-01
- Primary completion
- 2008-07-01
- Completion
- 2009-02-01
- First posted
- 2009-02-12
- Last updated
- 2013-08-30
- Results posted
- 2013-08-30
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT00842023. Inclusion in this directory is not an endorsement.