NCT00835900

An Alternative Dosing Schedule of Varenicline for Smoking Cessation

Extended Varenicline for Smoking Cessation: A Pilot Study

• Status: Completed
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 60 (actual)
• Sponsor: Roswell Park Cancer Institute · Academic / Other
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Accepted

Summary

The purpose of this study is to explore the use of an prolonged alternative dosing schedule using varenicline for smoking cessation leading to greater quit rates and higher rates of continuous abstinence.

Detailed description

This pilot study will utilize a two group randomized design. Adult smokers who are motivated to quit smoking will be randomized to one of two treatment groups. Both groups will receive brief support counseling. During a one-week baseline and the 4-week pre-quit period smoking rate, smoking satisfaction, withdrawal, and craving will be assessed on a daily basis.

Conditions

• Smoking Cessation

Interventions

Type	Name	Description
DRUG	varenicline	variable dosing schedule
DRUG	placebo	placebo

Timeline

• Start date: 2009-03-01
• Primary completion: 2010-07-01
• Completion: 2015-07-01
• First posted: 2009-02-04
• Last updated: 2017-05-30
• Results posted: 2017-05-30

Locations

1 site across 1 country: United States