NCT00832312

Intraarticular Ozone Therapy for Pain Control in Osteoarthritis of the Knee

• Status: Terminated
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 20 (actual)
• Sponsor: Ben-Gurion University of the Negev · Academic / Other
• Sex: All
• Age: 50 Years – 75 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to determine whether an intraarticular injection of Ozone into the knee joint is an effective therapy for pain control in patients with osteoarthritis of the knee.

Detailed description

Ozone, as a gas made of three atoms of oxygen with a cyclic structure, has been used as a medical therapy from the mid ninetieth century. Today, this therapy is a recognized modality in many European and Latin American nations for orthopedic problems, infections, ischemic diseases, and skin problems. However, despite of this wide use internationally, there is minimal mention of this treatment modality in the Anglo-American literature. The present is the first of a series of studies planned to scientifically test the effectiveness of ozone as a main-stream therapy, introducing it to the Anglo-American literature. In this first study we will check whether intraarticular injections of Ozone into the knee joint are effective as a therapy for pain control in patients with osteoarthritis of the knee.

Conditions

• Osteoarthritis of the Knee

Interventions

Type	Name	Description
OTHER	ozone-oxygen mixture	10 cc of an ozone-oxygen mixture with ozone concentration 10000 mcg/L (10 mcg/ml)
OTHER	placebo (saline)	Injection of 1cc of saline into the knee joint

Timeline

• Start date: 2009-08-01
• Primary completion: 2016-07-01
• Completion: 2016-08-01
• First posted: 2009-01-30
• Last updated: 2016-07-28

Locations

1 site across 1 country: Israel