NCT00816231

Drug /Cue Interactions In Alcohol-Tobacco Comorbidity

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 244 (actual)
• Sponsor: H. Lee Moffitt Cancer Center and Research Institute · Academic / Other
• Sex: All
• Age: 21 Years – 55 Years
• Healthy volunteers: Accepted

Summary

The purpose of this study is to determine how people react to different combinations of alcohol and nicotine.

Detailed description

The present project will improve and expand upon previously published work in several ways. First, Study 1 will assess reactivity to alcohol and smoking cues in the same session. Second, both studies will include within-subjects design factors to manipulate alcohol and nicotine intake, as well as cue types. Third, craving indices will represent three important response domains: subjective, physiological, and behavioral (e.g., Niaura et al., 1991). Fourth, each study will evaluate a range of drinkers and smokers, which will provide maximal information concerning influences on alcohol and smoking cue reactivity across various subject populations. The proposed studies are not only important from a theory development perspective, but they will provide an excellent foundation for future laboratory-based and clinical research.

Conditions

• Nicotine Dependence

Interventions

Type	Name	Description
BEHAVIORAL	Tobacco	Five research sessions. Session 1: Questionnaires, interviews, computer task, medical evaluation. Sessions 2 - 5: Lab Sessions involving tobacco with brief summary at the end of the last session.
OTHER	Alcoholic Beverage	Five research sessions. Session 1: Questionnaires, interviews, computer task, medical evaluation. Sessions 2 - 5: Lab Sessions involving and alcohol with brief summary at the end of the last session.
OTHER	Placebo	Five research sessions. Session 1: Questionnaires, interviews, computer task, medical evaluation. Sessions 2 - 5: Lab Sessions involving placebo with brief summary at the end of the last session.

Timeline

• Start date: 2006-05-08
• Primary completion: 2014-03-01
• Completion: 2019-06-20
• First posted: 2009-01-01
• Last updated: 2019-09-06

Locations

1 site across 1 country: United States