NCT00798694

How Similar Are Changes to the Surface of the Eye When Two Different Glaucoma Eye Drops Are Used?

Ocular Surface Changes With Topical Prostaglandin Analog Therapy

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 58 (actual)
• Sponsor: Wills Eye · Academic / Other
• Sex: All
• Age: 21 Years
• Healthy volunteers: Not accepted

Summary

To determine whether one glaucoma eye drop is less likely to cause changes to the surface of the eye (conjunctiva) than another. The two different prostaglandins are Xalatan and Travatan Z.

Detailed description

Two groups will be entered into this study: group 1 will be naive to treatment and group 2 will be using Xalatan for at least one month before enrollment. Both groups will be using one drop at bedtime of Xalatan in the right eye and one drop at bedtime of Travatan Z in the left eye. Both of these drops are presently on the market and approved by the FDA for treatment of lowering eye pressure. Because this study will be masked, the examining clinician will not know what study drop each patient has been using.

Conditions

• Glaucoma

Interventions

Type	Name	Description
DRUG	Xalatan	one drop of Xalatan Ophthalmic Solution instilled in right eye at bedtime
DRUG	Travatan Z	one drop of Travatan Z Ophthalmic Solution instilled in left eye at bedtime

Timeline

• Start date: 2008-11-01
• Primary completion: 2011-01-01
• Completion: 2011-02-01
• First posted: 2008-11-26
• Last updated: 2018-07-12
• Results posted: 2018-07-12

Locations

1 site across 1 country: United States

Regulatory

• FDA-regulated drug study