NCT00788463

A Comparison of Beclomethasone Aqueous Spray and Aerosol Delivery Systems in Nasal Polyps

• Status: Completed
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 30 (actual)
• Sponsor: London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to determine if intranasal Beclomethasone delivered by aerosol or spray is more effective in treatment of nasal polyps.

Detailed description

Aqueous and aerosol delivery of intranasal corticosteroids has never been directly compared previously in patients with nasal polyps and it is unknown whether one is superior. This objective of this study is to compare the efficacy of intranasal beclomethasone by two different delivery systems, aerosol and aqueous spray in patients with nasal polyps. Primary endpoint is the difference in the overall quality of life as measured by the Rhinitis Quality of Life Questionnaire. The secondary endpoint is the change in Nasal Airflow Resistance as measured by rhinomanometry.

Conditions

• Nasal Polyps

Interventions

Type	Name	Description
DRUG	Intranasal Beclomethasone aerosol	Beclomethasone aerosol intranasal, 100ug each nostril, twice daily for 6 months.
DRUG	Intranasal Beclomethasone spray	Beclomethasone spray intranasal, 100ug each nostril, twice daily for 6 months.

Timeline

• Start date: 2006-11-23
• Primary completion: 2009-03-30
• Completion: 2011-11-30
• First posted: 2008-11-11
• Last updated: 2017-08-28

Locations

1 site across 1 country: Canada