Clinical Trials Directory

Trials / Withdrawn

WithdrawnNCT00771043

A Proof-of-Concept Study to Correlate Retinal Nerve Fiber Layer Changes in Patients With Multiple Sclerosis Treated With Natalizumab or Interferon Beta 1-a

Optical Coherence Tomography as a Measure of Neuroprotection in Patients With Relapsing-Remitting Multiple Sclerosis Receiving Natalizumab or Interferon Beta-1a

Status
Withdrawn
Phase
Phase 4
Study type
Interventional
Enrollment
0 (actual)
Sponsor
Biogen · Industry
Sex
All
Age
18 Years – 55 Years
Healthy volunteers
Not accepted

Summary

Phase IV, proof-of-concept, randomized, open-label, multi-center, two-arm, 9-month study to evaluate the neuroprotective effects of Natalizumab (TYSABRI®) or Interferon beta-1a (AVONEX®) treatments initiated at the time of acute optic neuritis (AON) as measured by RNFL thickness from Optical Coherence Tomography in patients with Relapsing Remitting Multiple Sclerosis (RRMS).

Conditions

Interventions

TypeNameDescription
DRUGTYSABRI and AVONEXTYSABRI and AVONEX treatment per package insert.

Timeline

Start date
2008-11-01
Primary completion
2009-08-01
Completion
2010-06-01
First posted
2008-10-10
Last updated
2024-06-03

Source: ClinicalTrials.gov record NCT00771043. Inclusion in this directory is not an endorsement.

A Proof-of-Concept Study to Correlate Retinal Nerve Fiber Layer Changes in Patients With Multiple Sclerosis Treated With (NCT00771043) · Clinical Trials Directory