Clinical Trials Directory

Trials / Completed

CompletedNCT00770666

Combination Medications vs. Patch Alone for Medically-Ill Smokers

Flexibly-Dosed Combination Pharmacotherapy Versus Standard-Dosed Nicotine Patch Alone for Smokers With Medical Illness

Status
Completed
Phase
Phase 4
Study type
Interventional
Enrollment
127 (actual)
Sponsor
University of Medicine and Dentistry of New Jersey · Academic / Other
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

Randomized clinical trial to evaluate a flexibly-dosed-3-medication combination for up to 6 months in smokers with medical illness

Detailed description

Subjects randomly received either nicotine patch alone for a 10-week, tapering course (n=64) or the combination of nicotine patch, nicotine oral inhaler, and bupropion for an ad-lib duration (n=63).

Conditions

Interventions

TypeNameDescription
DRUGNicotine patch, nicotine inhaler, bupropionPatch - 21 mg - taper as able Inhaler - as needed Bupropion SR 150 mg daily
DRUGNicotine patch21 mg daily for 6 weeks followed by 14 mg for 2 weeks and then 7 mg for 2 weeks

Timeline

Start date
2005-09-01
Primary completion
2007-12-01
Completion
2008-01-01
First posted
2008-10-10
Last updated
2008-10-10

Locations

1 site across 1 country: United States

Source: ClinicalTrials.gov record NCT00770666. Inclusion in this directory is not an endorsement.