NCT00764556

Phase II Study of Safety and Feasibility of Intensive Blood Glucose Control With Insulin on Acute Medical Wards

• Status: Completed
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 20 (actual)
• Sponsor: St George's, University of London · Academic / Other
• Sex: All
• Age: 40 Years
• Healthy volunteers: Not accepted

Summary

Patients with chronic obstructive pulmonary disease (COPD) are commonly admitted to hospital with exacerbations of their lung disease. A combination of the acute illness and treatment with oral steroids causes a rise in blood sugar. Patients with high blood sugar do worse than those with normal blood sugar. The aim of this study is to develop a safe and effective protocol for tight control of blood glucose with insulin on acute medical wards outside the intensive care environment. This will allow us to perform a formal trial to determine whether blood glucose control with insulin reduces death and complications from COPD exacerbations.

Conditions

• COPD
• Hyperglycemia

Interventions

Type	Name	Description
DRUG	Insulin	Intravenous insulin (actrapid) Subcutaneous insulin (aspart, glargine, detemir)

Timeline

• Start date: 2008-05-01
• Primary completion: 2009-05-01
• Completion: 2009-05-01
• First posted: 2008-10-02
• Last updated: 2009-10-14

Locations

1 site across 1 country: United Kingdom