NCT00762775

The Interaction Between Calcium and Vitamin D Intake

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 78 (actual)
• Sponsor: Winthrop University Hospital · Academic / Other
• Sex: Female
• Age: 45 Years – 85 Years
• Healthy volunteers: Accepted

Summary

We will study the relative importance of high calcium intake and vitamin D supplementation for calcium homeostasis, as determined by serum parathyroid hormone (PTH) and biochemical bone markers. We also intend to examine the interaction of vitamin D and calcium intake on calcium homeostasis. We hypothesize that optimal calcium supplementation and optimal vitamin D supplementation will lead to lower serum levels of PTH and markers of bone resorption compared with the placebo. We also theorize that when taken together, optimal calcium supplementation and optimal vitamin D intake will result in lower serum levels of PTH and bone markers compared with calcium or vitamin D taken alone.

Conditions

• Osteoporosis

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Calcium and vitamin D supplementation	Arm 1: 1,200 mg daily of calcium supplementation and placebo; Arm 2: 100 microgram daily of Vitamin D and placebo; Arm 3: 1,200 mg of calcium and 100 microgram of Vitamin D daily; Arm 4: placebos only.

Timeline

• Start date: 2008-11-01
• Primary completion: 2011-06-01
• Completion: 2011-06-01
• First posted: 2008-09-30
• Last updated: 2014-12-11

Locations

1 site across 1 country: United States