NCT00760045

Clinical Pharmacological Study of AL-43546 Ophthalmic Product in Subjects With Shortened Tear Film Break Up Time

• Status: Completed
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 40 (estimated)
• Sponsor: Alcon Research · Industry
• Sex: All
• Age: 20 Years – 64 Years
• Healthy volunteers: Accepted

Summary

The purpose of the study is to observe lacrimal fluid condition (tear film break-up time) chronologically after a single dose of AL-43546 ophthalmic products（0.15%, 0.25% and vehicle）and 0.1% sodium hyaluronate ophthalmic solution and compare lacrimal fluid retention time between them.

Conditions

• Dry Eye Disease

Interventions

Type	Name	Description
DRUG	Hydroxypropyl Guar Galactomannan	One drop per one time in both eyes, once daily (at each visit).One instillation daily in one period and a total of 4 instillations over 4 periods.
DRUG	0.1% sodium hyaluronate ophthalmic solution	One drop per one time in both eyes, once daily (at each visit).One instillation daily in one period and a total of 4 instillations over 4 periods.

Timeline

• Start date: 2008-08-01
• Primary completion: 2008-10-01
• First posted: 2008-09-25
• Last updated: 2010-01-06

Locations

1 site across 1 country: Japan