Clinical Trials Directory

Trials / Terminated

TerminatedNCT00745316

Oral Tonapofylline (BG9928) in Patients With Heart Failure and Renal Insufficiency

A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study to Assess the Safety and Tolerability of Oral Tonapofylline in Patients With Heart Failure and Renal Insufficiency

Status
Terminated
Phase
Phase 2
Study type
Interventional
Enrollment
34 (actual)
Sponsor
Biogen · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

The main purpose of this study is to determine the safety and tolerability of tonapofylline (BG9928) when given at different doses to patients with heart failure and renal insufficiency. This study will also explore: * Disease related quality-of-life * Exercise capacity * Renal function * Concomitant medications

Conditions

Interventions

TypeNameDescription
DRUGTonapofyllineOral Tonapofylline - 2 capsules bid
DRUGPlaceboOral placebo - 2 capsules bid

Timeline

Start date
2009-02-01
Primary completion
2010-01-01
Completion
2010-01-01
First posted
2008-09-03
Last updated
2023-09-11

Locations

30 sites across 1 country: United States

Source: ClinicalTrials.gov record NCT00745316. Inclusion in this directory is not an endorsement.