NCT00739713

Effects of Sea Buckthorn Oil on Dry Eye

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 100 (actual)
• Sponsor: University of Turku · Academic / Other
• Sex: All
• Age: 20 Years – 75 Years
• Healthy volunteers: Accepted

Summary

The objective is to study the effect of sea buckthorn oil on dry eye.

Detailed description

The objective is to study whether regular consumption of sea buckthorn berry oil can relieve the symptoms of dry eye syndrome. The study design is a parallel randomized double-blind placebo controlled trial. The participants daily consume sea buckthorn or placebo oil for 3 months. The dry eye symptoms will be monitored during the study using a validated questionnaire. In addition clinical dry eye tests are made by an ophthalmologist three time during the study. Samples will be taken for tear film lipid and cytokine analyses. Blood samples for the analyses of inflammatory markers are also obtained. The cytokine and other inflammation marker analyses are optional. The symptoms will be monitored and clinical tests made also 4 weeks after the participants have stopped consuming the study oils.

Conditions

• Dry Eye Syndromes

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Sea buckthorn (Hippophaë rhamnoides) oil	Dosage 2 g/d, frequency twice/d, duration 3 months
DIETARY_SUPPLEMENT	Placebo comparison	Placebo comparison, dosage 2 g/d, frequency twice/d, duration 3 months

Timeline

• Start date: 2008-09-01
• Primary completion: 2009-03-01
• Completion: 2009-03-01
• First posted: 2008-08-22
• Last updated: 2018-03-20

Locations

1 site across 1 country: Finland