NCT00720954

Rigid Thoracoscopy Versus CT-Guided Pleural Needle Biopsy

Rigid Thoracoscopy Versus CT-Guided Pleural Needle Biopsy For Diagnosis of Patients With Pleural Effusions: A Randomized Control Trial

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 124 (actual)
• Sponsor: Eskisehir Osmangazi University · Academic / Other
• Sex: All
• Age: 18 Years – 85 Years
• Healthy volunteers: Not accepted

Summary

The aim of this study is to compare the rigid thoracoscopy with CT-guided pleural needle biopsy by the diagnostic efficacy and safety in patients with pleural effusion.

Detailed description

Pleural needle biopsy with Abrams needle, which can be performed by all chest physicians, is a simple, safe and cheap method of obtaining tissue from pleura, but its diagnostic rate is between 7 % -72 %, \~ 50 %. Problems for Abrams needle are scattered tumoral involvement on pleura, blind performance, small tissue sampling, to tend to early and dense fibrosis and usually involvement of lower pleural surface and diaphragmatic pleura. Pleural needle biopsy with Abrams' needle, which can be performed by all chest physicians, if done with image guided and if this increase the diagnosis rate, the number of second procedure which is more expensive and hard will decrease. The study aims the comparison of rigid thoracoscopy with CT-guided pleural needle biopsy by the diagnostic efficacy and safety in patients with pleural effusion. It has been planned that a total of 120 patients accepted to the study who have pleural effusion at plain chest roentgenogram. All patients are being randomized after underwent contrast-enhanced CT. Undiagnosed patients of biopsy group are performed thoracoscopy and undiagnosed patients of thoracoscopy group followed up. Two groups will compare by age, sex, Karnofsky performance status (KPS), diagnosis and complication rate.

Conditions

• Pleural Effusion
• Pleural Diseases

Interventions

Type	Name	Description
PROCEDURE	Ct-guided pleural needle biopsy	Biopsy of pleura
PROCEDURE	Thoracoscopy	Biopsy of pleura

Timeline

• Start date: 2006-01-01
• Primary completion: 2008-06-01
• Completion: 2008-06-01
• First posted: 2008-07-23
• Last updated: 2008-07-23

Locations

1 site across 1 country: Turkey (Türkiye)