NCT00720525

Pulsatile and Steady State Hemodynamics in Diastolic Heart Failure

Diagnostic Value of Measures of Pulsatile Versus Steady State Hemodynamics in Diastolic Heart Failure

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 362 (actual)
• Sponsor: Klinikum Wels-Grieskirchen · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Over the past few years, there has been a growing appreciation that a large number of patients with heart failure have a relatively normal (or preserved) ejection fraction (NFNEF). Epidemiologically, HFNEF is most prevalent among elderly women, most of whom have hypertension, diabetes, or both and often coronary artery disease (CAD). Increased arterial stiffness and/or wave reflections have been described in the same patient groups. Therefore, the investigators speculate that pulsatile hemodynamics, representing arterial stiffness and/or arterial wave reflections, 1) may be altered in HFNEF patients, 2) this may contribute to pathophysiology of HFNEF, and 3) this may be used for the diagnosis of the syndrome.

Conditions

• Diastolic Heart Failure

Timeline

• Start date: 2008-04-01
• Completion: 2011-07-01
• First posted: 2008-07-22
• Last updated: 2011-07-18

Locations

1 site across 1 country: Austria