Clinical Trials Directory

Trials / Completed

CompletedNCT00716547

Safety and Efficacy of Two Dosages of Diractin® in Osteoarthritis (OA)

Multicenter, Randomized, Double-blind, Placebo- and Active-controlled Study of Safety and Efficacy of Two Dosages of Epicutaneously Applied Diractin® (Ketoprofen in Transfersome® Gel) for the Treatment of Osteoarthritis of the Knee

Status
Completed
Phase
Phase 3
Study type
Interventional
Enrollment
1,399 (actual)
Sponsor
IDEA AG · Industry
Sex
All
Age
46 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study is to provide replicated evidence of safety and efficacy of 50 mg and 100 mg ketoprofen in Diractin®.

Detailed description

The study will investigate safety and efficacy of 2 dosages of Diractin®at relieving the signs and symptoms of knee OA, including the primary endpoint of patient assessment of pain.

Conditions

Interventions

TypeNameDescription
DRUGketoprofen in Diractin®50 mg (b.i.d.)
DRUGketoprofen in Diractin®100 mg (b.i.d.)
DRUGPlacebob.i.d.
DRUGcelecoxib100 mg (b.i.d.)

Timeline

Start date
2008-05-01
Primary completion
2009-03-01
Completion
2009-05-01
First posted
2008-07-16
Last updated
2009-10-16

Locations

4 sites across 4 countries: Czechia, Germany, Poland, United Kingdom

Source: ClinicalTrials.gov record NCT00716547. Inclusion in this directory is not an endorsement.