NCT00709865

Study to Assess the Safety and Tolerability of IV Tonapofylline in Subjects With Acute Decompensated Heart Failure (ADHF) and Renal Insufficiency

A Randomized, Double-Blind, Placebo-Controlled, Parallel Group Study to Assess the Safety and Tolerability of Intravenous Tonapofylline in Subjects With Acute Decompensated Heart Failure and Renal Insufficiency

• Status: Completed
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 420 (actual)
• Sponsor: Biogen · Industry
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The purpose of the current study is to assess the safety and tolerability of intravenous tonapofylline.

Conditions

• Renal Insufficiency
• Congestive Heart Failure

Interventions

Type	Name	Description
DRUG	tonapofylline	IV
DRUG	Placebo	IV

Timeline

• Start date: 2008-07-31
• Primary completion: 2009-10-30
• Completion: 2009-12-31
• First posted: 2008-07-03
• Last updated: 2023-09-11

Locations

189 sites across 18 countries: United States, Argentina, Australia, Brazil, Bulgaria, Canada, Czechia, Finland, France, Germany, India, Israel, Italy, Netherlands, Poland, Romania, Russia, Sweden