NCT00705757

The Effects of Xalatan, Travatan and Lumigan on Skin Pigmentation Near the Eye

The Effects of Latanoprost, Bimatoprost and Travoprost on Periocular Skin Pigmentation

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 89 (actual)
• Sponsor: Summa Health System · Academic / Other
• Sex: All
• Age: 30 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to study changes in skin color that may be caused by using one of the three eye medicines: Xalatan, Travatan or Lumigan.

Detailed description

One uncommon side effect of prostaglandin eye drops is a change in color of the skin around the eyes, which is reversible. There are three different brands of the medicine which are equally effective in lowering eye pressure but their likelihood of changing skin color is unknown. Qualifying patients will be randomly assigned to use one of the three eye drops. We will take skin color measurements from several locations on the face over one year to measure pigmentation changes.

Conditions

• Glaucoma
• Application Site Pigmentation Changes

Interventions

Type	Name	Description
DRUG	latanoprost	Xalatan/latanoprost 0.005% ophthalmic solution one drop qhs for one year
DRUG	bimatoprost	Lumigan/bimatoprost 0.03% ophthalmic solution one drop qhs for one year
DRUG	travoprost	Travatan/travoprost 0.004% ophthalmic solution one drop qhs for one year

Timeline

• Start date: 2008-03-01
• Primary completion: 2011-04-01
• Completion: 2011-04-01
• First posted: 2008-06-26
• Last updated: 2016-01-18
• Results posted: 2016-01-18

Locations

2 sites across 1 country: United States