Clinical Trials Directory

Trials / Completed

CompletedNCT00699764

Safety of a Herpes Simplex Candidate Vaccine (gD2t) With MPL and Its Efficacy to Prevent Genital Herpes Disease

Safety of SmithKline Beecham Biologicals' Herpes Simplex Candidate Vaccine (gD2t) With MPL & Its Efficacy to Prevent Genital Herpes Disease in HSV Positive or Negative Consorts of Subjects With Genital Herpes Disease

Status
Completed
Phase
Phase 3
Study type
Interventional
Enrollment
2,491 (actual)
Sponsor
GlaxoSmithKline · Industry
Sex
All
Age
18 Years – 45 Years
Healthy volunteers
Accepted

Summary

The purpose of the study is to evaluate the safety of Herpes Simplex candidate vaccine (gD2t) with adjuvant and its efficacy to prevent genital herpes disease in HSV positive or negative consorts of subjects with genital herpes disease.

Detailed description

This study was monitored by a Data Safety Monitoring Board At the time of conduct of this study, the sponsor GlaxoSmithKline was known by its former name SmithKline Beecham

Conditions

Interventions

TypeNameDescription
BIOLOGICALHerpes simplex candidate vaccine- adjuvanted GSK208141Intramuscular injection, 3 doses
BIOLOGICALPlacebo injectionIntramuscular injection, 3 doses

Timeline

Start date
1996-03-01
Primary completion
1999-10-01
Completion
1999-10-01
First posted
2008-06-18
Last updated
2016-09-07

Source: ClinicalTrials.gov record NCT00699764. Inclusion in this directory is not an endorsement.