NCT00697385

The Use of Cyclokapron for Treatment and Management of Women With Bleeding Disorders

Open Label Continuation Study for the Use of Cyclokapron for Treatment and Management of Women With Bleeding Disorders

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 13 (actual)
• Sponsor: Mary M. Gooley Hemophilia Center · Academic / Other
• Sex: Female
• Age: 8 Years – 60 Years
• Healthy volunteers: Not accepted

Summary

The high percentage of failure using available non-surgical options to treat menorrhagia in women with bleeding disorders shows a continuing need for innovative treatments. This has led to development of this protocol in order to make available tranexamic acid as a potentially effective menorrhagia therapy option in women with an underlying bleeding disorder. We anticipate that Tranexamic Acid may be a beneficial choice for controlling menorrhagia in bleeding disorder patients.

Detailed description

Women with heavy periods and with a diagnosed bleeding disorders are prescribed cyclokapron pills to be taken during their periods. Their periods are assessed at 3 and 6 months by filling out a pictorial blood assessment chart. If the drug appears to be working with no adverse effects the patients can continue to take the medication as long as it is available with follow up with the investigator every 6 months.

Conditions

• vonWillebrand Disease
• Hemophilia
• Platelet Coagulation Disorders

Interventions

Type	Name	Description
DRUG	Cyclokapron	(2) 500mg tablets taken by mouth every 6-8 hours

Timeline

• Start date: 2003-04-01
• Primary completion: 2008-06-01
• Completion: 2008-06-01
• First posted: 2008-06-13
• Last updated: 2008-09-19

Locations

1 site across 1 country: United States