Trials / Completed
CompletedNCT00693680
Zinc Supplementation of Imipramine Therapy
The Role of Zinc in Therapy of Unipolar Depression
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 60 (actual)
- Sponsor
- Polish Academy of Sciences · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
Examination of the effect of zinc supplementation on imipramine therapy in major depression.
Detailed description
A placebo-controlled, double blind study of zinc supplementation in imipramine therapy was conducted in sixty, depressed patients fulfilling the DSM-IV criteria for major depression without psychotic symptoms. After a one week washout period, patients were randomized into two groups treated with imipramine and receiving once daily either placebo (n=30) or zinc supplementation (n=30) for 12 weeks.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DIETARY_SUPPLEMENT | Zincas Forte | 25 mgZn/day + imipramine (100-200mg/day) |
| DIETARY_SUPPLEMENT | Placebo | placebo + imipramine (100-200mg/day) |
Timeline
- Start date
- 2005-01-01
- Primary completion
- 2006-04-01
- Completion
- 2006-04-01
- First posted
- 2008-06-09
- Last updated
- 2008-06-13
Locations
1 site across 1 country: Poland
Source: ClinicalTrials.gov record NCT00693680. Inclusion in this directory is not an endorsement.