Trials / Completed
CompletedNCT00684736
Tryptophan, Serotonin and Kynurenine in Septic Shock
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 30 (actual)
- Sponsor
- Versailles Hospital · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
Septic shock is a major cause of mortality and morbidity worldwide. Serotonin (5-HT) is released by activated platelets into the circulation, and is mediator of endothelial dysfunction. 5-HT metabolism is known in immune system via specific 5-HT receptor, also in effects on the peripheral nervous system. Kinetic of 5-HT, tryptophan, kynurenine, MAO activity and IDO activity in human septic shock was never investigated.
Conditions
Timeline
- Start date
- 2004-06-01
- Primary completion
- 2007-04-01
- Completion
- 2008-04-01
- First posted
- 2008-05-28
- Last updated
- 2008-08-08
Locations
1 site across 1 country: France
Source: ClinicalTrials.gov record NCT00684736. Inclusion in this directory is not an endorsement.