NCT00676000

Randomized Trial of Interrupted Versus Continuous Vaginal Closure of Anterior Repair With Mesh

• Status: Withdrawn
• Phase: N/A
• Study type: Interventional
• Enrollment: 350 (estimated)
• Sponsor: Brigham and Women's Hospital · Academic / Other
• Sex: Female
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Vaginal prolapse is a common condition that is treated with surgical correction. Recently surgeons have been using mesh to augment the repair of vaginal prolapse. Common complications of this surgery include vaginal pain, pain during sex, infection or erosion of the mesh in the vagina. There are different ways to close the vaginal wall over the mesh used in these procedures. Currently, there is no accepted standard method of closing the vaginal wall. The purpose of this study is to find out the best way to close the surgical wound in the vagina. We will compare interrupted closure (separate stitches) to continuous closure (one long, running stitch). We hope to show in our study that one method of closure is better than the other.

Conditions

• Pain
• Dyspareunia
• Surgical Mesh

Interventions

Type	Name	Description
PROCEDURE	Interrupted vaginal closure	Horizontal mattress closure of vaginal mucosa over mesh
PROCEDURE	Continuous vaginal closure	Running closure of vaginal mucosa over mesh

Timeline

• Start date: 2008-04-01
• Primary completion: 2009-12-01
• First posted: 2008-05-12
• Last updated: 2009-03-19