NCT00666029

Implications for Treatment of the Metabolic Syndrome

• Status: Completed
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 40 (actual)
• Sponsor: University Hospital Southampton NHS Foundation Trust · Academic / Other
• Sex: All
• Age: 18 Years – 75 Years
• Healthy volunteers: Accepted

Summary

To characterize features of metabolic syndrome in volunteers. To undertake a randomised trial to determine whether treatment with a statin improves muscle microvascular blood flow.

Detailed description

To characterise features of the metabolic syndrome, including body fat, insulin sensitivity, and liver fat together with muscle micorvascular blood flow. To undertake a randomised controlled trial of atorvastatin 40 mg. o.d for 6 months to determine whether any of the above measures change with treatment.

Conditions

• Metabolic Syndrome

Interventions

Type	Name	Description
DRUG	atorvastatin	40 m.g. o.d. tablets for 6 months
DRUG	placebo	Placebo

Timeline

• Start date: 2006-02-01
• Primary completion: 2008-02-01
• Completion: 2008-02-01
• First posted: 2008-04-24
• Last updated: 2019-01-23
• Results posted: 2016-06-09