Clinical Trials Directory

Trials / Completed

CompletedNCT00660660

Local Phase IV, Gastroesophageal Reflux Disease (GERD) Sleep Study US

A Multicenter, Randomized, Double-Blind, Placebo-Controlled Efficacy Study Comparing 4 Weeks of Treatment With Esomeprazole 20 mg qd to Placebo qd in Patients With Heartburn and Sleep Disturbances Associated With Gastroesophageal Reflux Disease (GERD)

Status
Completed
Phase
Phase 4
Study type
Interventional
Enrollment
276 (actual)
Sponsor
AstraZeneca · Industry
Sex
All
Age
18 Years – 85 Years
Healthy volunteers
Not accepted

Summary

The purpose of this research study is to compare the safety and effectiveness (how well the medicine works) of esomeprazole (study drug) to placebo (a capsule that does not contain any medication) taken daily in relieving nighttime heartburn and problems sleeping in patients with gastroesophageal reflux disease (GERD).

Conditions

Interventions

TypeNameDescription
DRUGEsomeprazoleNexium 20 mg administered once daily as 22.3 mg of esomeprazole magnesium hydrate
DRUGPlaceboonce daily

Timeline

Start date
2008-04-01
Primary completion
2008-07-01
Completion
2008-07-01
First posted
2008-04-17
Last updated
2015-03-02
Results posted
2015-03-02

Locations

45 sites across 1 country: United States

Source: ClinicalTrials.gov record NCT00660660. Inclusion in this directory is not an endorsement.