NCT00626210

Modafinil Treatment for Sleep/Wake Disturbances in Older Adults

• Status: Terminated
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 2 (actual)
• Sponsor: VA Palo Alto Health Care System · Federal
• Sex: All
• Age: 50 Years
• Healthy volunteers: Not accepted

Summary

Modafinil, trade named Provigil, is a medication approved by the Food and Drug Administration for the treatment of narcolepsy, obstructive sleep apnea/hypopnea syndrome, and shift work sleep disorder. Each of these problems is characterized by difficulty sleeping at night and excessive daytime sleepiness. Modafinil is prescribed during the day to counteract this sleepiness. The idea behind this treatment is that sleepiness that leads to napping during the day prevents a patient from being tired or sleepy enough to get good sleep at night. This study is designed to determine if the medication can "reset" participants' sleep/wake rhythm to a more normal rhythm.

Conditions

• Insomnia
• Sleep Initiation and Maintenance Disorders
• Alzheimer Disease

Interventions

Type	Name	Description
DRUG	modafinil	100-400 mg daily for 4 weeks

Timeline

• Start date: 2008-02-01
• Primary completion: 2011-04-01
• Completion: 2012-10-01
• First posted: 2008-02-29
• Last updated: 2019-10-28
• Results posted: 2014-10-30

Locations

1 site across 1 country: United States