Clinical Trials Directory

Trials / Completed

CompletedNCT00625495

Study Comparing the Effects of Esomeprazole Adminstered Orally and Intravenously on Basal and Pentrigastrin-stimulated Acid Output in Subjects With Symptoms of Gastroesophageal Reflux Disease (GERD)

An Open, Randomised Two Way Crossover Study Comparing the Effects of 40mg of Esomeprazole Adminstered Orally and Intravenously as a 3 Minute Injection on Basal and Pentrigastrin-stimulated Acid Output in Subjects With Symptoms of Gastroesophageal Reflux Disease (GERD)

Status
Completed
Phase
Phase 4
Study type
Interventional
Enrollment
60 (actual)
Sponsor
AstraZeneca · Industry
Sex
All
Age
18 Years – 75 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study is to examine the effects of Nexium at a dose of 40mg administered orally compared to intravenously on the maximum acid output in subjects with symptoms of Gastroesophageal reflux disease (GERD).

Conditions

Interventions

TypeNameDescription
DRUGEsomeprazole40mg Intravenous infusion over 3 minutes
DRUGEsomeprazole40mg Oral

Timeline

Start date
2002-09-01
Primary completion
2002-11-01
Completion
2002-11-01
First posted
2008-02-28
Last updated
2011-01-24

Source: ClinicalTrials.gov record NCT00625495. Inclusion in this directory is not an endorsement.