NCT00624221

Study of Eye Bank Pre-cut Donor Grafts for Endothelial Keratoplasty

A Prospective, Randomized, Single Center Study Evaluating Use of Surgeon- and Eye Bank-prepared Donor Tissue for Descemet's Stripping and Endothelial Keratoplasty, a Type of Cornea Transplant

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 40 (actual)
• Sponsor: Cornea Research Foundation of America · Academic / Other
• Sex: All
• Age: 21 Years
• Healthy volunteers: Not accepted

Summary

Descemet's stripping with endothelial keratoplasty (DSEK) is a cornea-sparing transplant technique that replaces only the diseased endothelial cell layer of the patient's cornea. The DSEK technique requires lamellar dissection of the donor tissue prior to implantation in the patient's eye. The surgeon usually dissects the donor cornea with a microkeratome at the time of surgery. Recently some eye banks have begun to pre-cut the donor graft as an added service. The purpose of this study was to compare outcomes with eye bank pre-cut and surgeon-dissected donor grafts for DSEK.

Conditions

• Fuchs Endothelial Dystrophy
• Corneal Edema

Interventions

Type	Name	Description
PROCEDURE	Descemet's stripping endothelial keratoplasty	Small incision corneal transplant procedure to treat dysfunctional endothelium.

Timeline

• Start date: 2006-01-01
• Primary completion: 2007-10-01
• Completion: 2007-11-01
• First posted: 2008-02-27
• Last updated: 2016-04-27
• Results posted: 2010-03-12

Locations

1 site across 1 country: United States