NCT00620867

Efficacy and Safety of Celecoxib Versus Ibuprofen in the Treatment of Osteoarthritis of the Knee (United States)

A Study of the Efficacy and Tolerability of Once Daily Celebrex (Celecoxib) and Three Times Daily Ibuprofen vs. Placebo in the Treatment of Subjects With Osteoarthritis of the Knee

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 393 (actual)
• Sponsor: Pfizer's Upjohn has merged with Mylan to form Viatris Inc. · Industry
• Sex: All
• Age: 40 Years
• Healthy volunteers: Not accepted

Summary

To compare the efficacy and safety of celecoxib versus ibuprofen in subjects with osteoarthritis (OA) of the knee.

Conditions

• Osteoarthritis, Knee

Interventions

Type	Name	Description
DRUG	Ibuprofen	800 mg oral tablet three time daily with meals for 6 weeks
DRUG	celecoxib	200 mg oral capsule once daily with morning meal for 6 weeks
OTHER	placebo	matched placebo orally for 6 weeks

Timeline

• Start date: 2002-10-01
• Primary completion: 2003-03-01
• Completion: 2003-03-01
• First posted: 2008-02-22
• Last updated: 2021-02-21

Locations

33 sites across 1 country: United States