NCT00615628

Inheritance of Osteosarcoma & Paget's Disease Through Chromosome 18:

Inheritance of Osteosarcoma & Paget's Disease Through Chromosome 18: Examination of Osteosarcoma Tissue Samples From Two Family Members for Loss of Heterozygosity in the Chromosome 18 Region, Genetically Linked With Paget's Disease of Bone

• Status: Terminated
• Phase: —
• Study type: Observational
• Enrollment: 8 (actual)
• Sponsor: State University of New York - Upstate Medical University · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Not accepted

Summary

Researchers have previously demonstrated loss of heterozygosity in a region on chromosome 18q, associated with osteogenic sarcomas in bone affected by Paget's disease. The loci used in this study are specifically described by those authors as showing loss of heterozygosity in 6 of 7 affected families.

Detailed description

As above, no additional information

Conditions

• Osteosarcoma
• Paget's Disease

Timeline

• Start date: 2002-04-01
• Primary completion: 2009-12-01
• Completion: 2009-12-01
• First posted: 2008-02-14
• Last updated: 2013-05-30

Locations

1 site across 1 country: United States