Clinical Trials Directory

Trials / Completed

CompletedNCT00609193

Functional and Neurochemical Brain Changes in First-episode Bipolar Mania

Functional and Neurochemical Brain Changes in First-episode Bipolar Mania Following Successful Treatment With Lithium or Quetiapine

Status
Completed
Phase
Study type
Observational
Enrollment
81 (actual)
Sponsor
University of Cincinnati · Academic / Other
Sex
All
Age
12 Years – 35 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study is to use magnetic resonance imaging (MRI) to examine brain structure, function and chemistry in people with bipolar disorder who are being treated with either quetiapine or lithium. Both of these medicines are FDA-approved to treat mania in adults and lithium is also FDA approved in children; quetiapine is commonly used in children with mania, but is not FDA approved for this indication in this age group.

Conditions

Interventions

TypeNameDescription
DRUGlithiumstandard clinical care
DRUGquetiapinestandard clinical care

Timeline

Start date
2008-01-01
Primary completion
2015-06-01
Completion
2015-07-01
First posted
2008-02-06
Last updated
2015-12-07

Locations

1 site across 1 country: United States

Source: ClinicalTrials.gov record NCT00609193. Inclusion in this directory is not an endorsement.