NCT00607295

Efficacy and Safety of Clino-san on Vaginal Dryness of Breast Cancer Patients

Prospective Randomized Study on Efficacy and Safety of Clino-san® in the Management of Vaginal Dryness in Breast Cancer Patients

• Status: Completed
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 98 (actual)
• Sponsor: Seoul National University Hospital · Academic / Other
• Sex: Female
• Age: 20 Years
• Healthy volunteers: Not accepted

Summary

1. Although after treatment for breast cancer such as chemotherapy or hormonal therapy, urogenital atrophy is common, the patients are seldomly treated for several reasons. Management of this problem is important for improving quality of life. 2. "Clino-san" is a kind of vaginal lubricant with pH 5 which is similar pH of premenopausal vaginal discharge. After randomization of patients, they are treated with Clino-san or placebo 3 times/week for 12 weeks. 3. We check the vaginal symptoms, vag dryness severity score, and ultrasonography at baseline, 4, 8, and 12 weeks of treatment.

Conditions

• Breast Cancer
• Vaginal Atrophy

Interventions

Type	Name	Description
DRUG	clino-san vaginal lubricant	Clino-san 2ml vaginal application 3 times per week for 12 weeks

Timeline

• Start date: 2007-12-01
• Primary completion: 2008-12-01
• Completion: 2009-02-01
• First posted: 2008-02-05
• Last updated: 2010-07-27

Locations

1 site across 1 country: South Korea