Clinical Trials Directory

Trials / Completed

CompletedNCT00606060

BAY14-2222 Continuous Infusion in Surgeries

Safety and Efficacy of Continuous Infusion of Recombinant Factor VIII - Sucrose-formulated (BAY 14 2222) Concentrate in Patients With Hemophilia A Undergoing Major Elective Surgery.

Status
Completed
Phase
Phase 3
Study type
Interventional
Enrollment
15 (actual)
Sponsor
Bayer · Industry
Sex
Male
Age
12 Years – 65 Years
Healthy volunteers
Not accepted

Summary

Phase III study, to evaluate the efficacy and safety of continuous infusion of rFVIII-FS in the treatment of patients with hemophilia A undergoing major elective surgery by achieving the required therapeutic concentrations.

Conditions

Interventions

TypeNameDescription
DRUGKogenate (BAY14-2222)100 IU/mL (250 IU/vial nominal potency) continuous infusion over 6-11 days in 12 patients. 400 IU/mL (1000 IU/vial nominal potency) continuous infusion over 6-11days in 3 patients.

Timeline

Start date
2004-07-01
Completion
2005-05-01
First posted
2008-02-01
Last updated
2010-04-13

Locations

1 site across 1 country: Israel

Source: ClinicalTrials.gov record NCT00606060. Inclusion in this directory is not an endorsement.