NCT00595699

Escitalopram Treatment of Major Depression in Patients With Temporal Lobe Epilepsy

Escitalopram Treatment of Major Depression in Patients With Temporal Lobe Epilepsy. A Double-blind, Placebo-controlled Study.

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 8 (actual)
• Sponsor: Conrad, Erich J., M.D. · Academic / Other
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

This is a research study evaluating the use of escitalopram (Lexapro®) for the treatment of major depression in subjects with temporal lobe epilepsy. The purpose of the study is to measure the severity and change in depressive and anxiety symptoms after 10 weeks of study treatment with escitalopram or placebo as measured by certain rating scales and questionnaires. In addition, the study will measure the frequency of seizures using a patient diary during the study. Finally, the study will assess the change in the quality of life using rating scales.

Conditions

• Major Depression
• Temporal Lobe Epilepsy

Interventions

Type	Name	Description
DRUG	escitalopram	10 mg daily for the first week followed by an increase to 20 mg daily for the remainder of the study
DRUG	placebo	Placebo

Timeline

• Start date: 2006-11-01
• Primary completion: 2009-12-01
• Completion: 2009-12-01
• First posted: 2008-01-16
• Last updated: 2011-07-18

Locations

1 site across 1 country: United States