NCT00589836

Assessment of Left Ventricular Torsion by Echocardiography Study

Assessment of LV Torsion by Tissue Doppler Echocardiography

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 20 (actual)
• Sponsor: The Cleveland Clinic · Academic / Other
• Sex: All
• Age: 18 Years – 70 Years
• Healthy volunteers: Accepted

Summary

The purpose of this study is to learn about the twisting or wringing motion of the heartbeat called Left Ventricular Torsion (LV Torsion) which can be seen on ultrasound.

Detailed description

This study is designed to characterize the myocardial torsional behavior in patients with a variety of cardiac pathologies. Simple and inexpensive methods for measurement of LV torsion could facilitate more widespread investigation of LV torsion, which might reveal significant relationships between torsional alterations and clinical outcomes and eventually lead to routine clinical application. Recently, Doppler tissue imaging (DTI) has been shown to accurately reflect myocardial velocity24,25 with better temporal resolution than MRI.26 Investigators hypothesize therefore that DTI might be used for quantification of LV rotation and torsion of the human heart. The purpose of the present study was to examine the accuracy of a novel method with DTI for quantifying the LV torsion in humans and tagged MRI as the reference standard.

Conditions

• Hypertrophic Cardiomyopathy

Timeline

• Start date: 2005-06-01
• Primary completion: 2008-04-01
• Completion: 2008-04-01
• First posted: 2008-01-10
• Last updated: 2018-02-05
• Results posted: 2018-02-05

Locations

1 site across 1 country: United States