Trials / Unknown
UnknownNCT00588718
A Biologic Validation of Biomarkers of Progressive NEC & Sepsis
A Biologic Sample Study for the Validation of Biomarkers of Progressive NEC & Sepsis
- Status
- Unknown
- Phase
- —
- Study type
- Observational
- Enrollment
- 740 (estimated)
- Sponsor
- R. Lawrence Moss · Academic / Other
- Sex
- All
- Age
- 72 Hours – 28 Weeks
- Healthy volunteers
- Not accepted
Summary
Necrotizing enterocolitis (NEC) is a severe, sometimes life-threatening inflammation of the intestine that occurs most often in premature babies. If it progresses, the wall of the intestine may perforate, spilling bacteria and stool into the abdomen. Parts or all of the intestine may die. Despite 30 years of clinical studies, the cause of NEC remains unknown. In this study, we will be conducting an independent case-control validation study to verify the diagnostic and prognostic biomarker panels, develop validated biomarkers on boisensors in preparation for prospective validation studies, and conduct independent prospective validation of biosensor based biomarker panels on clinical samples.
Conditions
Timeline
- Start date
- 2007-04-01
- Primary completion
- 2019-12-01
- Completion
- 2019-12-01
- First posted
- 2008-01-09
- Last updated
- 2018-03-09
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT00588718. Inclusion in this directory is not an endorsement.