NCT00587314

The Effect of Ablation Therapy on Barrett's Esophagus

• Status: Enrolling By Invitation
• Phase: —
• Study type: Observational
• Enrollment: 600 (estimated)
• Sponsor: Mayo Clinic · Academic / Other
• Sex: All
• Age: 18 Years – 90 Years
• Healthy volunteers: Not accepted

Summary

To assess the effect of ablative therapy (Photodynamic Therapy or Radiofrequency ablation ) on Barrett's Esophagus

Detailed description

To assess the effect of ablation therapy on Barrett's esophagus. Proposal Ablation therapy is an FDA approved treatment to decrease cancer risk in Barrett's esophagus mucosa. This is being performed in our Barrett's Esophagus Unit on a regular basis. However, the longterm outcomes of this therapy is not established and there are patients who have been treated who later re-develop Barrett's mucosa. This study will allow us store tissue samples that can later be used to assess the effect of ablative therapy on Barrett's esophagus.

Conditions

• Barrett's Esophagus
• Early Esophageal Adenocarcinoma

Interventions

Type	Name	Description
OTHER	Biopsy	Biopsies for research purposes will be obtained when returning for clinically indicated surveillance of Barrett's Esophagus

Timeline

• Start date: 2004-01-01
• Primary completion: 2029-01-01
• Completion: 2029-01-01
• First posted: 2008-01-07
• Last updated: 2026-03-11

Locations

1 site across 1 country: United States