NCT00571233

Biomarker Study for Heart Failure in Children With Single Ventricle Physiology

Identification of Biomarkers for Heart Failure in Children With Single Ventricle Physiology

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 71 (actual)
• Sponsor: University of California, San Francisco · Academic / Other
• Sex: All
• Age: 1 Month – 6 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to determine if children with heart disease where there is only one pumping chamber("ventricle") have proteins (biomarkers") in the blood that can be used to monitor the function of their heart.

Detailed description

We will investigate whether levels of blood proteins in children with well-functioning hearts with one ("single") ventricle are similar to levels of these blood proteins in children with two ventricles. For children with hearts with a single ventricle, we will examine blood proteins at various levels of heart function. To assess blood protein levels, we will collect small (6 mL) samples of blood. Heart function will be determined by existing clinical scoring systems. Enrolled patients will receive an echocardiogram, which is a dynamic ultrasound picture of the beating heart.

Conditions

• Tricuspid Atresia
• Hypoplastic Left Heart Syndrome
• Unbalanced AV Canal

Timeline

• Start date: 2007-02-01
• Primary completion: 2011-12-01
• Completion: 2015-01-01
• First posted: 2007-12-11
• Last updated: 2015-05-14

Locations

1 site across 1 country: United States