Trials / Terminated
TerminatedNCT00567437
Utility of Exercise-induced N-terminal (NT) Pro-brain Natriuretic Peptide Levels in Predicting Prognosis in Asymptomatic Aortic Stenosis
Utility of Exercise-induced NT-pro-brain Natriuretic Peptide Levels in Predicting Prognosis in Asymptomatic Aortic Stenosis
- Status
- Terminated
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 110 (estimated)
- Sponsor
- Duke University · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Accepted
Summary
One hundred patients with moderate to severe asymptomatic aortic stenosis (AS) will be asked to exercise on a treadmill. NT-pro-BNP levels will be drawn before and after exercise. Changes in NT-pro-BNP levels will be correlated to outcomes at one year. In the pilot phase an additional 10 control subjects without AS will be enrolled to document the control response of NT-pro-BNP elevations with exercise.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| OTHER | NT-pro-BNP levels | pre- and post-exercise NT-pro-BNP levels |
Timeline
- Start date
- 2007-12-01
- Completion
- 2008-12-01
- First posted
- 2007-12-05
- Last updated
- 2012-10-24
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT00567437. Inclusion in this directory is not an endorsement.