NCT00567411

Comparison of the Alpha-2 Agonists for Prevention of Intraocular Pressure Elevation After Selective Laser Trabeculoplasty

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 43 (estimated)
• Sponsor: Walter Reed Army Medical Center · Federal
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The purpose of the study is to compare the safety and efficacy of two drops used to lower eye pressure when given prior to a glaucoma laser procedure.

Detailed description

This is a prospective randomized double blind trial of patients undergoing selective laser trabeculoplasty for primary open angle glaucoma and ocular hypertension. Enrolled patients are randomized to receive one drop of brimonidine 0.1% in one eye and one drop of apraclonidine 0.5% in the fellow eye. The trabecular meshwork in both eyes of each enrolled patient is treated 360 degrees at the same sitting. Intraocular pressure is measured in each eye one hour before applying the study medications and at one hour and one week after laser surgery.

Conditions

• Glaucoma
• Ocular Hypertension

Interventions

Type	Name	Description
DRUG	brimonidine 0.1%	1 drop, 1 hour prior to selective laser trabeculoplasty (SLT)
DRUG	Apraclonidine 0.5%	1 drop applied 1 hour prior to SLT

Timeline

• Start date: 2006-08-01
• Completion: 2009-06-01
• First posted: 2007-12-05
• Last updated: 2007-12-05

Locations

1 site across 1 country: United States